Dr. David Meinke
Regents Professor Emeritus
Dept. of Plant Biology, Ecology, and Evolution
301 Physical Sciences, Stillwater, OK 74078-3013, USA
Research
I have longstanding research interests in the developmental and molecular genetics of multicellular eukaryotes, the establishment of Arabidopsis thaliana as a model organism for plant biology, and the isolation and characterization of embryo-defective mutants of Arabidopsis, which have provided valuable insights into hundreds of essential genes with diverse functions in plant growth and development. Most recently, my research has focused on the developmental consequences of a loss of chloroplast translation in Arabidopsis and the relationship between genotype and phenotype for an essential protein involved in fatty acid biosynthesis. I am also interested in human genetics and medical genomics, the emergent fields of genetic testing and personalized medicine, and the complex interactions between genetics, technology, and public policy. Most urgently, I believe that public policy should be guided whenever possible by scientific evidence, and not by personal or political ideologies. Because I am retired, I am no longer accepting graduate students into my research program. But my passion for genetics in particular, and science in general, remains unabated.
Recent Publications
For an expanded list of publications, click here.
Meinke DW (2019) Genome-wide identification of EMBRYO-DEFECTIVE (EMB) genes required for growth and development in Arabidopsis. New Phytol doi: 10.1111/nph.16071.
Parker N, Wang Y, Meinke D (2016) Analysis of Arabidopsis accessions hypersensitive to a loss of chloroplast translation. Plant Physiol 172: 1862-1875.
Oellrich A, Walls RL, Cannon EK, Cannon SB, Cooper L, Gardiner J, Gkoutos GV, Harper L, He M, Hoehndorf R, Jaiswal P, Kalberer SR, Lloyd JP, Meinke D, Menda N, Moore L, Nelson RT, Pujar A, Lawrence CJ, Huala E (2015) An ontology approach to comparative phenomics in plants. Plant Methods 11:10.
Parker N, Wang Y, Meinke D (2014) Natural variation in sensitivity to a loss of chloroplast translation in Arabidopsis. Plant Physiol 166: 2013-2027.
Meinke D (2013) Large-scale mutant analysis of seed development in Arabidopsis thaliana. In: Becraft PW (ed) Seed Genomics, pp 5-20. Wiley-Blackwell, Ames, Iowa.
Meinke DW (2013) A survey of dominant mutations in Arabidopsis thaliana. Trends Plant Sci. 18: 84-91
Lloyd J, Meinke D (2012) A comprehensive dataset of genes with a loss-of-function mutant phenotype in Arabidopsis thaliana. Plant Physiol 158:1115-1129.
Muralla R, Lloyd J, Meinke D (2011) Molecular foundations of reproductive lethality in Arabidopsis thaliana. PLoS ONE 6: e28398.
Bryant N, Lloyd J, Sweeney, C, Myouga, F, Meinke D (2011) Identification of nuclear genes encoding chloroplast-localized proteins required for embryo development in Arabidopsis thaliana. Plant Physiol 155: 1678-1689.
Koornneef M, Meinke D (2010) The development of Arabidopsis as a model plant. Plant J. 61:909-921.